In a striking revision of his long-term outlook, MicroStrategy executive chairman Michael Saylor has projected Bitcoin could reach $21 million per coin by 2046. The prediction came during his keynote at BTC Prague 2025, where he cited unprecedented geopolitical and regulatory developments accelerating cryptocurrency adoption.

From $13M to $21M: Evolving Bullish Thesis

Saylor's latest forecast marks a significant increase from his $13 million prediction made at Bitcoin 2024. The executive attributes this adjustment to recent developments including:

• U.S. political shifts following the 2024 election

• Establishment of a national Bitcoin reserve

• Three major crypto bills advancing through Congress

"What's occurred in these past months would have been unimaginable a year ago," Saylor remarked, pointing to 【state-level Bitcoin adoption】 and White House support as game-changers.

The Trump Effect on Crypto Policy

The executive highlighted how the current administration's pro-crypto stance has created a ——paradigm shift—— in digital asset regulation. "We anticipated political support, but not strategic national reserves or declarations about America becoming the Bitcoin superpower," Saylor noted.

Recent legislative progress includes:

1. The Genius Act (stablecoin regulation)

2. Digital Asset Market Clarity Act

3. Bitcoin Reserve Act

MicroStrategy's Growing Bitcoin Treasury

Saylor's optimism coincides with MicroStrategy's continued BTC accumulation, now holding 【592,100 Bitcoin】 worth approximately $35 billion at current prices. The company recently added $1 billion worth of BTC during Middle East tensions.

——"This isn't speculation; it's a fundamental belief in Bitcoin as property,"—— Saylor stated when questioned about the firm's storage methods, which remain undisclosed for security reasons.

Self-Custody Debate Continues

The conference also spotlighted ongoing discussions about asset security, with Trezor reporting over 5,000 attendees exploring self-custody solutions. This follows Saylor's controversial 2024 comments questioning personal custody, which he later walked back after community backlash.

Trezor's Danny Sanders observed: "The Prague crowd demonstrates deepening technical engagement—developers and newcomers alike are prioritizing open-source tools and financial sovereignty."

As the event concluded, Saylor's revised prediction underscored Bitcoin's evolving narrative—from speculative asset to geopolitical chess piece in what he calls "the most significant monetary transformation since the gold standard."